Non-football related stuff that really makes your day

[Panoptes]

Did you read that BILL C.?

Now come on Diabetes and Cancer research.....move it along now.

[Sharkbait]

What G sais...^

[Panoptes]

Whats up SB?

How you feelin?

[SeattleLionsFan]

Bill do you know if that's for remitting relapsing and progressive mS?

[The Cat]

Bill do you know if that's for remitting relapsing and progressive mS?

sslf, I was at my nerusorgeons's office today. I have to have some pretty intricate work done in thenear future, to stop the dead nerves in my back from continuing to wrap themselves around my spinal cord. these nerves went amok after them myelin coating wore off. Anyway he tells me from what he received is that this will not only stop progression, but actually reverse it....it's his take this is for all ms types. the process apparently fools the immune system back to thinking everything is normal so that it stops attacking healthy tissue. Yeah this is big......really big.

Tell your dad to hang in there.

[-Deborah-]

Bill, that sounds like some scary work you're having done soon. You're in my prayers.

[The Cat]

Bill, that sounds like some scary work you're having done soon. You're in my prayers.

walk in the park Deb...I had it done 11 years ago in the states on the upper area of my back. The difference this time is its happened in the middle area, so my mobility is decreasing rapidly...but I will come through just fine. It only means havy pain meds and another missed forum trip.
Thanksfor the thoughts though.

SLF, I put on my journalists hat and phoned the researchers today.
This is the news release they published in the Can Journal of Medicine ...Hope this helps....

McGill/JGH researchers successfully reverse multiple sclerosis in animals
Published: Tuesday, August 11, 2009 - 12:16 in Health & Medicine
Related images
(click to enlarge)

Claudio Calligaries/McGill University


A new experimental treatment for multiple sclerosis (MS) completely reverses the devastating autoimmune disorder in mice, and might work exactly the same way in humans, say researchers at the Jewish General Hospital Lady Davis Institute for Medical Research and McGill University in Montreal. MS is an autoimmune disease in which the body's own immune response attacks the central nervous system, almost as if the body had become allergic to itself, leading to progressive physical and cognitive disability.
The new treatment, appropriately named GIFT15, puts MS into remission by suppressing the immune response. This means it might also be effective against other autoimmune disorders like Crohn's disease, lupus and arthritis, the researchers said, and could theoretically also control immune responses in organ transplant patients. Moreover, unlike earlier immune-supppressing therapies which rely on chemical pharamaceuticals, this approach is a personalized form of cellular therapy which utilizes the body's own cells to suppress immunity in a much more targeted way.
GIFT15 was discovered by a team led by Dr. Jacques Galipeau of the JGH Lady Davis Institute and McGill's Faculty of Medicine. The results were published August 9 in the prestigious journal Nature Medicine.
GIFT15 is composed of two proteins, GSM-CSF and interleukin-15, fused together artificially in the lab. Under normal circumstances, the individual proteins usually act to stimulate the immune system, but in their fused form, the equation reverses itself.
"You know those mythical animals that have the head of an eagle and the body of a lion? They're called chimeras. In a lyrical sense, that's what we've created," said Galipeau, a world-renowned expert in cell regeneration affiliated with the Segal Cancer Centre at the Jewish General and McGill's Centre for Translational Research. "GIFT15 is a new protein hormone composed of two distinct proteins, and when they're stuck together they lead to a completely unexpected biological effect."
This effect, explained Galipeau, converts B-cells -- a common form of white blood cell normally involved in immune response -- into powerful immune-suppressive cells. Unlike their better-known cousins, T-cells, naturally-occurring immune-suppressing B-cells are almost unknown in nature and the notion of using them to control immunity is very new.
"GIFT15 can take your normal, run-of-the-mill B-cells and convert them -- in a Superman or Jekyll -Hyde sort of way -- into these super-powerful B-regulatory cells," Galipeau explained. "We can do that in a petri dish. We took normal B-cells from mice, and sprinkled GIFT15 on them, which led to this Jekyll and Hyde effect.
"And when we gave them back intravenously to mice ill with multiple sclerosis, the disease went away."
MS must be caught in its earliest stages for the best effect, Galipeau cautioned, and clinical studies are needed to test the treatment's efficacy and safety in humans. No significant side-effects showed up in the mice, he said, and the treatment was fully effective with a single dose.
"It's easy to collect B-cells from a patient," he added. "It's just like donating blood. We purify them in the lab, treat them with GIFT15 in a petri dish, and give them back to the patient. That's what we did in mice, and that's what we believe we could do in people

[DanO]

Amazing.

GO LIONS "09" !!!!!!!!!

[Sharkbait]

Whats up SB?

How you feelin?

Gettin' stronger every day, brother. Can see the end of the tunnel sometime in Oct/Nov.

[Sharkbait]

sslf, I was at my nerusorgeons's office today. I have to have some pretty intricate work done in thenear future, to stop the dead nerves in my back from continuing to wrap themselves around my spinal cord. these nerves went amok after them myelin coating wore off. Anyway he tells me from what he received is that this will not only stop progression, but actually reverse it....it's his take this is for all ms types. the process apparently fools the immune system back to thinking everything is normal so that it stops attacking healthy tissue. Yeah this is big......really big.

Tell your dad to hang in there.

Prayers back atcha , Bill.

[SeattleLionsFan]

Thanks Bill. Great info.

[Panoptes]

Gettin' stronger every day, brother. Can see the end of the tunnel sometime in Oct/Nov.

Nice

[Panoptes]

BILL C.,

Get er done.

Good luck and get well soon.

[Panoptes]

Headed out to Big Bear Lake, CA for 3 days, 2 nights.

http://thm-a03.yimg.com/image/189d86b1cf758fa4

pands

I actually look forward to returning to my recorded DET and KC first pre-c games while under new leadership.

I'll be looking primarily for GUN's influence on the way the D players flow to the ball.

[romster]

Happy Birthday G!